VSys is managed best with a single file server share which all or most users will use together. VSys will use approx. 50MB on this share at the very outside. The contents of this share do not need to be regularly backed up, as no data is stored here.
For ex-VolunteerWorks organizations, you already have a common file share for its operation, and VSys does not require any more rights to this share than VolunteerWorks did. In fact VSys can operate without write access to the share once the program is fully operational.
For other organizations, you'll need to establish a share which all users who will work with VSys have at least read and execute permissions on.