Get to the Profile editor by clicking on a person's name from the various Person lookup tools, the list of all people in a project, or from the list of people in a delegation.
Use the Add link to add an assignment or right-click on the list of assignments to add, edit or delete assignments.
Use the Show past link to view past assignments or Hide past to remove them.
Use the Cancel... link to cancel assignments for a specific time window, e.g. a volunteer on leave, or to cancel all future assignments.